After the release of Zv9 in July 2010, the GRC has taken over the improvement and maintenance of the zebrafish genome assembly. In the four years since, the GRC has been working on filling gaps with new clone sequence and improving the positioning of assembly components with the help of optical mapping, Strandseq (M. Hills, PMID: 24028793) and additional meiotic mapping (GAPmap, D. Stemple, unpublished). The resulting improved clone path was supplemented with a new whole genome shotgun assembly WGS31, based on a combination of Illumina and capillary reads from double-haploid Tuebingen individuals, leading to the release of the integrated zebrafish genome assembly GRCz10.

Getting Data

• GRCz10 (latest major release): FTP
• Information on regions under review: FTP
• Annotated clone assembly problems: FTP
• Current Tiling Path Files (TPFs)

GRCz10

• Release date: September 17, 2014
• Release type: Major
• Release notes: GRCz10 is the first update to the zebrafish genome assembly released by the GRC. All chromosomes and scaffolds have been assigned new accessions. More than 4000 genome issues were resolved.
• Assembly accession: GCF_000002035.5 (RefSeq) / GCA_000002035.3 (GenBank)

Zv9

• Release date: Jul 22, 2010
• Release type: Major
• Release notes: This assembly was the last assembly released by the Wellcome Trust Sanger Institute. The GRC are now working to close gaps and represent variation where appropriate.
• Assembly accession: GCF_000002035.4 (RefSeq) / GCA_000002035.2 (GenBank)